产品货号：
Z31201
中文名称：
E2F4抗体
英文名称：
Anti-E2F4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-E2F4 Antibody |
| 指标别名 | E2F 4;E2F4;Transcription factor E2F4 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | E2F4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human E2F4 Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site,5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. |
| 实际分子量 | 60KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Transcription factor E2F4 is a protein that in humans is encoded by the E2F4 gene.The protein encoded by this gene is a member of the E2F family of transcription factors.This gene is mapped to 16q22.1.The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses.These domains include a DNA binding domain,a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP),a transactivation domain enriched in acidic amino acids,and a tumor suppressor protein association domain which is embedded within the transactivation domain.This protein binds to all three of the tumor suppressor proteins pRB,p107 and p130,but with higher affinity to the last two.Additionally,it plays an important role in the suppression of proliferation-associated genes,and its gene mutation and increased expression may be associated with human cancer. |
| Uniprot ID | Q16254 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：E2F4抗体，E2F4单抗，Anti-E2F4 Antibody